Skip to main content
Log in

Toward online quantification of tracheal stenosis from videobronchoscopy

  • Original Article
  • Published:
International Journal of Computer Assisted Radiology and Surgery Aims and scope Submit manuscript

Abstract

Purpose

Lack of objective measurement of tracheal obstruction degree has a negative impact on the chosen treatment prone to lead to unnecessary repeated explorations and other scanners. Accurate computation of tracheal stenosis in videobronchoscopy would constitute a breakthrough for this noninvasive technique and a reduction in operation cost for the public health service.

Methods

Stenosis calculation is based on the comparison of the region delimited by the lumen in an obstructed frame and the region delimited by the first visible ring in a healthy frame. We propose a parametric strategy for the extraction of lumen and tracheal ring regions based on models of their geometry and appearance that guide a deformable model. To ensure a systematic applicability, we present a statistical framework to choose optimal parametric values and a strategy to choose the frames that minimize the impact of scope optical distortion.

Results

Our method has been tested in 40 cases covering different stenosed tracheas. Experiments report a non- clinically relevant \(9\,\%\) of discrepancy in the calculated stenotic area and a computational time allowing online implementation in the operating room.

Conclusions

Our methodology allows reliable measurements of airway narrowing in the operating room. To fully assess its clinical impact, a prospective clinical trial should be done.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9

Similar content being viewed by others

Notes

  1. http://tinyurl.com/kmqmfys.

  2. Bellvitge Hospital, Barcelona. Sampling size for clinical trial.

References

  1. Asari KV (2000) A fast and accurate segmentation technique for the extraction of gastrointestinal lumen from endoscopic images. Med Eng Phys 22(2):89–96

  2. Begnaud A, Connett JE, Harwood EM, Jantz MA, Mehta HJ (2014) Measuring central airway obstruction: What do bronchoscopists do? Ann Am Thorac Soc 12(1):85–90

  3. Brouns M, Jayaraju ST, Lacor C, De Mey J, Noppen M, Vincken W, Verbanck S (2007) Tracheal stenosis: a flow dynamics study. J Appl Phys 102(3):1178–1184

    Google Scholar 

  4. Brown Robert H, Herold Christian J, Hirshman Carol A (1991) In vivo measurements of airway reactivity using high resolution computed tomography. Am Rev Respir Dis 144:208–212

    Article  CAS  PubMed  Google Scholar 

  5. Carden Kelly A, Boiselle Philip M, Waltz David A, Ernst Armin (2005) Tracheomalacia and tracheobronchomalacia in children and adults an in-depth review. CHEST J 127(3):984–1005

    Article  Google Scholar 

  6. Muller K (1989) Statistical power analysis for the behavioral sciences. Technometrics 31(4):499–500

  7. Colt H, Murgu S (2012) Bronchoscopy and central airway disorders. Elsevier, New York

    Google Scholar 

  8. Dörffel WV, Fietze I (1999) A new bronchoscopic method to measure airway size. Eur Respir J 14(4):783–788

    Article  PubMed  Google Scholar 

  9. Dunnett CW (1980) A multiple comparison procedure for comparing several treatments with a control. J Am Stat Assoc 50:1096–1121

    Article  Google Scholar 

  10. Forkert Lutz, Watanabe Hiroshi, Sutherland Kenneth, Vincent Sandra, Fisher John T (1996) Quantitative videobronchoscopy: a new technique to assess airway caliber. Am J Respir Crit Care Med 154(6):1794

    Article  CAS  PubMed  Google Scholar 

  11. Freeman W, Adelson EH (1991) The design and use of steerable filters. IEEE Trans Pattern Anal Mach Intell 13(9):891–906

    Article  Google Scholar 

  12. Gallo G, Torrisi A (2012) Lumen detection in endoscopic images: a boosting classification approach. Int J Adv Intell Syst 5(1–2):127–134

    Google Scholar 

  13. Garcia-Barnes J, Gil D, Badiella L, Hernandez-Sabate A, Carreras F, Pujades S, Martí E (2010) A normalized framework for the design of feature spaces assessing the left ventricular function. IEEE Trans Med Imaging 29(3):733–745

    Article  CAS  PubMed  Google Scholar 

  14. Gil D, Radeva P (2005) Extending anisotropic operators to recover smooth shapes. Comput Vis Image Underst 99:110–125

    Article  Google Scholar 

  15. Hayashi A, Takanashi S (2012) New method for quantitative assessment of airway calibre using a stereovision fibreoptic bronchoscope. Br J Anaesth 108(3):512–516

    Article  CAS  PubMed  Google Scholar 

  16. Heimann T, van Ginneken B (2009) Comparison and evaluation of methods for liver segmentation from ct datasets. IEEE Trans Med Imaging 28(8):1251–1265

    Article  PubMed  Google Scholar 

  17. Hein E, Rutter M (2006) New perspectives in pediatric airway reconstruction. Int Anesthesiol Clin 44(1):51

    Article  PubMed  Google Scholar 

  18. Helferty James P, Zhang Chao, McLennan Geoffrey, Higgins William E (2001) Videoendoscopic distortion correction and its application to virtual guidance of endoscopy. IEEE Trans Med Imaging 20(7):605–617

    Article  CAS  PubMed  Google Scholar 

  19. Hernàndez-Sabaté A (2009) Exploring arterial dynamics and structures in intravascular ultra sound sequences. PhD thesis, Universitat Autònoma de Barcelona

  20. Jowett Nathan, Weersink Robert A, Zhang Kai, Campisi Paolo, Forte Vito (2008) Airway luminal diameter and shape measurement by means of an intraluminal fiberoptic probe: a bench model. Arch Otolaryngol Head Neck Surg 134(6):637

    Article  PubMed  Google Scholar 

  21. Kass M, Witkin A, Terzopoulos D (1988) Snakes: active contour models. Int J Comput Vis 1(4):321–331

    Article  Google Scholar 

  22. Lee Karen S, Sun Maryellen RM, Ernst Armin, Feller-Kopman David, Majid Adnan, Boiselle Phillip M (2007) Comparison of dynamic expiratory ct with bronchoscopy for diagnosing airway malacia: a pilot evaluation. Chest 131:758–764

    Article  PubMed  Google Scholar 

  23. Masters IB, Eastburn MM (2005) A new method for objective identification and measurement of airway lumenin paediatric flexible videobronchoscopy. Thorax 60(8):652

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  24. McFawn PK, Forkert L, Fisher JT (2001) A new method to perform quantitative measurement of bronchoscopic images. Eur Respir J 18(5):817–826

    Article  CAS  PubMed  Google Scholar 

  25. Miller Jr RG (1997) Beyond ANOVA: basics of applied statistics. CRC Press, London

  26. Mori Kensaku, Deguchi Daisuke, Sugiyama Jun, Suenaga Yasuhito, Toriwaki Jun-ichiro, Maurer CR, Takabatake Hirotsugu, Natori Hiroshi (2002) Tracking of a bronchoscope using epipolar geometry analysis and intensity-based image registration of real and virtual endoscopic images. Med Image Anal 6(3):321–336

    Article  CAS  PubMed  Google Scholar 

  27. Murgu S, Colt H (2013) Subjective assessment using still bronchoscopic images misclassifies airway narrowing in laryngotracheal stenosis. Interact Cardiovasc Thorac Surg 16(5):655–660

    Article  PubMed Central  PubMed  Google Scholar 

  28. Murgu S, Colt HG (2009) Morphometric bronchoscopy in adults with central airway obstruction: case illustrations and review of the literature. Laryngoscope 119(7):1318–1324

    Article  PubMed  Google Scholar 

  29. Myer C 3rd, O’connor D, Cotton R (1994) Proposed grading system for subglottic stenosis based on endotracheal tubesizes. Ann Otol Rhinol Laryngol 103(4 Pt 1):319

    Article  PubMed  Google Scholar 

  30. Norwood S, Vallina VL, Short K (2000) Incidence of tracheal stenosis and other late complications after percutaneous tracheostomy. Ann Surg 232(2):233

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  31. Nouraei SAR, McPartlin DW, Nouraei SM, Patel A, Ferguson C, Howard DJ, Sandhu GS (2006) Objective sizing of upper airway stenosis: a quantitative endoscopic approach. Laryngoscope 116:12–17

    Article  CAS  PubMed  Google Scholar 

  32. Odry BL, Kiraly AP, Slabaugh GG, Novak CL, Naidich DP, Lerallut JF (2008) Active contour approach for accurate quantitative airway analysis. In: Medical Imaging. International Society for Optics and Photonics, pp 691613–691613

  33. Phee SJ, Ng WS, Chen IM, Seow-Choen F, Davies BL (1998) Automation of colonoscopy. ii. visual control aspects. IEEE Eng Med Biol Mag 17(3):81–88

    Article  CAS  PubMed  Google Scholar 

  34. Polverosi R, Vigo M, Baron S, Rossi G (2001) Evaluation of tracheobronchial lesions with spiral ct: comparison between virtual endoscopy and broncoscopy. Radiol Med 102:313–319

    CAS  PubMed  Google Scholar 

  35. Rozycki HJ, Van Houten ML, Elliott GR (1996) Quantitative assessment of intrathoracic airway collapse in infants and children with tracheobronchomalacia. Pediatr Pulmonol 21(4):241–245

    Article  CAS  PubMed  Google Scholar 

  36. Tubiana M, Nagataki S, Feinendegen LE (2008) Computed tomography and radiation exposure. N Engl J Med 358(8):850

  37. Sánchez C, Bernal J, Gil D, Sánchez FJ (2014) On-line lumen centre detection in gastrointestinal and respiratory endoscopy. In: Clinical image-based procedures. Translational Research in Medical Imaging, vol 8361. Springer, Switzerland, pp 31–38

  38. Sánchez C, Gil D, Rosell A, Andaluz A, Sánchez FJ (2013) Segmentation of tracheal rings in videobronchoscopy combining geometry and appearance. VISAPP 1:153–161

    Google Scholar 

  39. Sucar LE, Gillies DF (1990) Knowledge-based assistant for colonscopy. In: Proceedings of the 3rd international conference on industrial and engineering applications of artificial intelligence and expert systems, vol 2. ACM, pp 665–672

  40. Thrun S, Leonard JJ (2008) Simultaneous localization and mapping. Springer, New York, pp 871–889

    Google Scholar 

  41. Vergnon JM, Costes F, Bayon MC, Emonot A (1995) Efficacy of tracheal and bronchial stent placement on respiratory functional tests. Chest 107(3):741–746

    Article  CAS  PubMed  Google Scholar 

  42. Wieand S, Gail MH, James BR, James KL (1989) A family of nonparametric statistics for comparing diagnostic markers with paired or unpaired data. Biometrika 76(3):585–592

    Article  Google Scholar 

  43. Zabulis X, Argyros AA, Tsakiris DP (2008) Lumen detection for capsule endoscopy. In: IROS. IEEE/RSJ International Conference on IEEE, pp 3921–3926

Download references

Conflict of interest

The authors declare that they have no conflict of interest.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Carles Sánchez.

Additional information

This work was supported by Spanish Project TIN2012-33116, Fundació Marató TV3 20133510 and FIS-ETES PI09/90917. D. Gil is supported by the Serra Hunter program of the Catalan Government.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sánchez, C., Bernal, J., Sánchez, F.J. et al. Toward online quantification of tracheal stenosis from videobronchoscopy. Int J CARS 10, 935–945 (2015). https://doi.org/10.1007/s11548-015-1196-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11548-015-1196-z

Keywords

Navigation