Elsevier

Medical Hypotheses

Volume 33, Issue 2, October 1990, Pages 75-78
Medical Hypotheses

Why the incidence of cancer is increasing: the role of ‘light pollution’

https://doi.org/10.1016/0306-9877(90)90182-EGet rights and content

Abstract

At present, cancer is responsible for almost half of all deaths among women 45–64 years of age, and about 30% of all deaths among men in the same age group (1). This high rate represents a marked increase from the end of the last century (2), and it probably has a multifactorial etiology. Air pollution, smoking, diet, alcohol, occupational exposures and stress are all considered as possible etiologic and risk factors (3). We put forward a hypothesis that one of the most important etiologic factors in the rapid growth rate of cancer is the change of light exposure that took place in the last 100 years, especially in the developed countries. Increased light exposure acting through the pineal gland reduces melatonin production, thereby diminishing the non-specific oncostatic effects of the pineal gland.

References (29)

  • I Berenblum et al.

    A new quantiative approach to the study of the stages of chemical carcinogenesis in the mouse's skin

    Br. J. Cancer

    (1947)
  • JW Berg

    World-wide variations in cancer incidence as clues to cancer origins

  • E Tapp

    The pineal gland in malignancy

  • AB Lerner et al.

    Isolation of melatonin, the pineal gland factor that lightens melanocytes

    J. Amer. Chem. Soc.

    (1958)
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