Clinical Research
Multicenter randomly controlled trial on acupoint injection therapy with Chinese herbal medicines for oculomotor paralysis

https://doi.org/10.1016/S1003-5257(13)60003-3Get rights and content

Abstract

Objective

To evaluate the clinical effect of acupoint injection therapy for paralysis of oculomotor nerve with Chinese herbal medicines.

Methods

A total number of 456 patients from 3 centers with paralysis of oculomotor nerve were randomly divided into an acupoint injection group and a control group with 228 cases each. Patients in the acupoint injection group were treated with injection of Chinese herbal medicines to Jīngmíng (

BL 1), Yángbái (
GB 14), Sìbái (
ST 2), Tóngziliáo (
GB 1) on the affected side, and Gĕnshū (
BL 18) on both sides, Compound Angelica Injection was the main drug, and the corresponding acupoints and other injection drugs were also used according to differentiation of syndrome. Patients in the control group were treated with common western medicine. The treatment was given once a day, 10 times constituted one course with 3 days of interval. After 3 courses, the effect was assessed. TCM syndrome score, eyeball movement degree, the sizes of oculi rimae and pupil of the two groups were recorded before and after treatment.

Results

The effective rate of acupoint injection group was 91.7% (209/228), and that of the control group was 73.6% (168/228). There was statistical significance in comparing the difference between the two groups (P<0.05). TCM syndrome scores of the two groups after the treatment became less obviously than those before the treatment (P<0.01, P<0.05), the score of acupoint injection group was more reduced than that of the control group (P<0.05). Eyeball movement degree and oculi rimae were enlarged and the pupil reduced in the affected eye in both groups after the treatment (all P<0.05). The musculus rectus medialis for the eyeball movement in the acupoint injection group was more improved than that of the control group, and the oculi rimae was bigger in the acupoint injection group than that in the control group (both P<0.05).

Conclusion

Acupoint injection therapy with Chinese herbal medicines has assured effect on the treatment of oculomotor paralysis.

Section snippets

First author: GUO Shu-qin (1956-), female, chief physician.

Research field: integrative medicine for the treatment of endocrine diseases.

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Cited by (0)

First author: GUO Shu-qin (1956-), female, chief physician.

Research field: integrative medicine for the treatment of endocrine diseases.

Supported by designated project of 2008 Scientific Plan of TCM Integrative Medicine of Hebei Administration of TCM: 2008080

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