Abstract
We have developed a microviscometer analyzing the fluid dynamics in a single channel glass microfluidic chip with a closed end. The device is able to test sample volumes of a few microliters by inserting one drop in the inlet. The fluid enters the channel driven by capillary pressure and an optical sensor registers the motion. The equation that describes the fluid dynamics is function of the channel geometry, atmospheric pressure, fluid viscosity, and capillary pressure. Knowing the first two, the last parameters can be obtained as fitting parameters from the meniscus position as a function of time plot. We have successfully tested Newtonian fluids with different viscosities and capillary pressure.
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Alvares MC, Ayuso DP, Granda MG (2008) Critical points in the fabrication of microfluidic devices on glass substrates. Sensors Actuat B 130:436–448. doi:10.1016/j.snb.2007.09.043
Chevalier J, Ayelaa F (2008) Microfluidic on chip viscometers. Rev Sci Instrum 79:076–102. doi:10.1063/1.2940219
Das S, Waghmare PR, Mitra SK (2012) Early regimes of capillary filling. Phys Rev E 86:067–301. doi:10.1103/PhysRevE.86.067301
Han Z, Tang X, Zheng B (2007) A PDMS viscometer for microliter Newtonian fluid. J Micromech Microeng 17:1828–1834. doi:10.1088/0960-1317/17/9/011
Jasper JJ (1972) The surface tension of pure liquid compounds. J Phys Chem Ref Data 1(4):841–1010. doi:10.1063/1.3253106
Lee J, Tripathi A (2005) Intrinsic viscosity of polymers and biopolymers measured by microchip. Anal Chem 77:7137–7147
Lucas R (1918) Ueber das zeitgesetz des kapillaren aufstiegs von flssigkeiten. Kolloid-Zeitschrift 23:15–22. doi:10.1007/BF01461107
Marsh JA, Garoff S, Dussan V EB (1993) Dynamic contact angles and hydrodynamics near a moving contact line. Phys Rev Lett 70:2778–2781. doi:10.1103/PhysRevLett.70.2778
Nguyen NT (2006) Fundamentals and Aplications of Microfluidics. Artech House integrated microsystems series, Artech House
Nguyen NT, Yap YF, Sumargo A (2008) Microfluidic rheometer based on hydrodynamic focusing. Meas Sci Technol 19(8):085–405. doi:10.1088/0957-0233/19/8/085405
Parkin SJ, Knöner G, Nieminen TA, Heckenberg NR, Rubinsztein-Dunlop H (2007) Picoliter viscometry using optically rotated particles. Phys Rev E 76:041–507. doi:10.1103/PhysRevE.76.041507
Phan VN, Nguyen NT, Yang C, Joseph P, Djeghlaf L, Bourrier D, Gue AM (2010) Capillary filling in closed end nanochannels. Langmuir 26:13–251. doi:10.1021/la1010902
Pipe C, McKinley G (2009) Microfluidic rheometry. Mech Res Commun 36:110–120. doi:10.1016/j.mechrescom.2008.08.009
Radiom M, Chand WK, Yang C (2010) Capillary filling with the effect of pneumatic pressure of trapped air. Microfluid Nanofluid 9:65–75. doi:10.1007/s10404-009-0527-1
Saha AA, Mitra SK (2009) Effect of dynamic contact angle in a volume of fluid (VOF) model for a microfluidic capillary flow. J Colloid Interface Sci 339(2):461–480. doi:10.1016/j.jcis.2009.07.071
Srivastava N, Burns MA (2006) Analysis of non Newtonian liquids using a microfluidic capillary viscometer. Anal Chem 78:1690–1696. doi:10.1021/ac0518046
Srivastava N, Davenport RD, Burns MA (2005) Nanoliter viscometer for measuring blood plasma. Anal Chem 77:383–392. doi:10.1021/ac0494681
Waghmare PR, Mitra SK (2012) A comprehensive theoretical model of capillary transport in rectangular microchannels. Microfluid Nanofluid 12:53–63. doi:10.1007/s10404-011-0848-8
Washburn EW (1921) The dynamics of capillary flow. Phys Rev 17:273–283. doi:10.1103/PhysRev.17.273
White F (1998) Fluid Mechanics. McGraw-Hill, New York
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N. Morhell: Fellowship holder Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET)
H. Pastoriza: Researcher at Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET)
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Morhell, N., Pastoriza, H. A single channel capillary microviscometer. Microfluid Nanofluid 15, 475–479 (2013). https://doi.org/10.1007/s10404-013-1162-4
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DOI: https://doi.org/10.1007/s10404-013-1162-4