Elsevier

Neuroscience Letters

Volume 476, Issue 3, 7 June 2010, Pages 142-145
Neuroscience Letters

Catecholamine plasma levels following immune stimulation with rabies vaccine in dogs selected for their paw preferences

https://doi.org/10.1016/j.neulet.2010.04.016Get rights and content

Abstract

Epinephrine and norepinephrine plasma levels were assessed in dogs in relation to paw preference following an immune challenge with rabies vaccine. The results showed that both catecholamines increased after the vaccine administration, confirming the main role of the sympathetic nervous system in the modulation activity between the brain and the immune system. Moreover, ambidextrous dogs showed a significantly higher increase of epinephrine levels 8 days after immunization with respect to right- and left-pawed dogs, suggesting that the biological activity of this molecule could be key for a different immune response with regard to laterality.

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Acknowledgments

This research is part of the project: “Cerebral lateralization in dogs” supported by the University of Bari, Italy through a grant to A.Q.

We are most grateful to the Section of Infectious Diseases at Department of Veterinary Public Health, Bari, Italy for technical support during catecholamines determination.

We thank Merial, Italy for providing rabies vaccines.

References (25)

  • V.M. Sanders et al.

    Norepinephrine, the beta-adrenergic receptor, and immunity

    Brain Behav. Immun.

    (2002)
  • O. Schulte-Herbrüggen et al.

    Tumor necrosis factor-a and interleukin-6 regulates secretion of brain-derived neurotrophic factor in human monocytes

    J. Neuroimmunol.

    (2005)

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